Yang Likun

1. Personal profile

Name: Yang Likun

Education background: Doctor

Title: Lecturer

Office telephone: 0532-85906579

Email: yanglikun@ouc.edu.cn

2.Teaching course

《Metabolic Biochemistry》

3. Research direction

Neurohormonal regulation of developmental processes in Marine model animals; Model of hormone-receptor interaction and its functional evolution in chordates

4.Research results

He has presided over the National Natural Science Foundation Youth Project, the Shandong Provincial Natural Science Foundation Youth Project, and the China Postdoctoral Foundation. Participating in the national key research and development programs and other special projects.

Representative papers:

1. Yang, L. K., Zhang, J., Liu, D., Han, T. Y., Qin, Q. S., Wang, A. Q., Dong, B.*. (2023). Ancestral glycoprotein hormone and its cognate receptor present in primitive chordate ascidian: Molecular identification and functional characterization. International Journal of Biological Macromolecules. 229: 401-412.

2. Yang, L. K.^#, Hou, Z. S.^#, & Tao, Y. X.* (2021). Biased signaling in naturally occurring mutations of G protein-coupled receptors associated with diverse human diseases. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1867(1): 165973.

3. Yang, L. K. & Tao, Y. X.* (2020). Alanine scanning mutagenesis of the DRYxxI motif and intracellular loop 2 of human melanocortin-4 receptor. International Journal of Molecular Sciences, 21(20): 7611.

4. Yang, L. K., Zhang, Z. R., Wen, H. S., & Tao, Y. X.* (2019). Characterization of channel catfish (Ictalurus punctatus) melanocortin-3 receptor reveals a potential network in regulation of energy homeostasis. General and Comparative Endocrinology, 277: 90-103.

5. Yang, L. K. & Tao, Y. X.* (2017). Biased signaling at neural melanocortin receptors in regulation of energy homeostasis. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1863: 2486-2495.