Lu Zhiyi

1.Personal Profile

Name: Lv Zhiyi

Education: Doctor

Title: Associate Professor

Email: lvzhiyi@ouc.edu.cn

2.Teaching course 

Structural biochemistry

3.Research direction

His research direction is molecular biology and biophysical mechanism of cell coordination during embryonic development. Drosophila melanogaster and ascidian were used as experimental models to study the dynamic changes and regulation of cell cycle, cytoskeleton and cell junction during embryonic development by means of molecular genetics, biochemistry, microscopic imaging and quantitative analysis.

4.Research results

Host topic:

1. General program of NSFC: Molecular mechanism of DOCK/ELMO complex inducing the initiation of cell top base polarity

No.: 32070786 (2021.1-2024.12)

2. Young expert of Taishan Scholars in Shandong Province 2020-2024 Cell biological mechanism of the development of ascidian notochord

3. Young Talent III of Ocean University of China 2020-2022 Cytoskeleton regulation of animal embryo development

Published articles:

Zhiyi Lv*, Jan Rosenbaum, Stephan Mohr, Xiaozhu Zhang, Deqing Kong, Helen Preiß;, Sebastian Kruss, Karen Alim; Timo Aspelmeier, Jörg Großhans*. The emergent Yo-yo movement of nuclei driven by cytoskeletal remodeling in pseudo-synchronous mitotic cycles, Current Biology (2020). 30(13)

Zhiyi Lv, Jorge de-Carvalho, Ivo A. Telley, Jörg Großhans*. Drosophila syncytial embryo: a simple tissue model for studying cytoskeletal mechanics and dynamics. Journal of Cell Science. 134(4):jcs246496

Zhiyi Lv, Jan Rosenbaum, Timo Aspelmeier, Jörg Großhans*: A molecular guillotine reveals an interphase function of Kinesin-5. Journal of Cell Science 01/2018; 131(3)., DOI:10.1242/jcs.210583

Anja Schmidt#, Zhiyi Lv#, Jörg Großhans: ELMO and Sponge specify subapical restriction of Canoe and formation of the subapical domain in early Drosophila embryos. Development 12/2017; 145(2):dev.157909., DOI:10.1242/dev.157909

Zhiyi Lv, Jörg Großhans*: A Radial Actin Network in Apical Constriction. Developmental Cell 11/2016; 39(3):280-282., DOI:10.1016/j.devcel.2016.10.017