杨立昆

一、个人简介

姓名：杨立昆

学历：博士

职称：讲师

办公电话：0532-85906579

邮箱：yanglikun@ouc.edu.cn

二、在海德教授课程名称

《代谢生物化学》

三、研究方向

海洋模式动物发育过程的神经激素调控机制；脊索动物激素—受体相互作用模式及其功能演化

四、研究成果

主持国家自然科学基金青年项目，山东省自然科学基金青年项目，中国博士后基金面上项目等；参与国家重点研发计划专项等项目。

代表性论文：

1. Yang, L. K., Zhang, J., Liu, D., Han, T. Y., Qin, Q. S., Wang, A. Q., Dong, B.*. (2023). Ancestral glycoprotein hormone and its cognate receptor present in primitive chordate ascidian: Molecular identification and functional characterization. International Journal of Biological Macromolecules. 229: 401-412.

2. Yang, L. K.^#, Hou, Z. S.^#, & Tao, Y. X.* (2021). Biased signaling in naturally occurring mutations of G protein-coupled receptors associated with diverse human diseases. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1867(1): 165973.

3. Yang, L. K. & Tao, Y. X.* (2020). Alanine scanning mutagenesis of the DRYxxI motif and intracellular loop 2 of human melanocortin-4 receptor. International Journal of Molecular Sciences, 21(20): 7611.

4. Yang, L. K., Zhang, Z. R., Wen, H. S., & Tao, Y. X.* (2019). Characterization of channel catfish (Ictalurus punctatus) melanocortin-3 receptor reveals a potential network in regulation of energy homeostasis. General and Comparative Endocrinology, 277: 90-103.

5. Yang, L. K. & Tao, Y. X.* (2017). Biased signaling at neural melanocortin receptors in regulation of energy homeostasis. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1863: 2486-2495.